All forms of focal alopecia, including alopecia areata, alopecia totalis and alopecia universalis are curable.
Alopecia areata and its heavy forms alopecia totalis and alopecia universalis are multiple-factor diseases. That’s why there is no a universal sure remedy against baldness and it will hardly be found.
Heavy forms of circumscribed alopecia take a great deal of patience and long treatment. It is necessary for patient and doctor to reactivate growth of hair by joint efforts and to prevent its possible loss.
Hair follicles on the grown bald areas are vegetative and remain completely viable during 10-12 years after hair loss. Then its possibilities to initiate growth of hair are gradually going down as a result of developing fibrosis of skin (including cutaneous elastoidosis), which leads to an atrophy of follicles.
Enzyme 5-alpha-reductase is in an organism in prostate, in sebaceous glands and in hair follicles. The main task of enzyme is convertion of testosterone, circulation in blood, in active form of dihydrotestosterone (DH?). So, what do hair bulbs transform testosterone in DH? for if this leads to hair loss? However, there is a deep biological sense in it. Hair has sexual significance, and it needs to know, should it grow in this area of body or not. And it depends on who is the owner of body: man or woman.
For example, follicles located on the chin, will react on DH? positively, because chin is a man’s sign. Excess of estrogen will force the same follicles to inhibit growth of hair. As long hair is an adornment of women, not of men, hair follicles located on a head are stimulated by estrogen and suppressed by androgens. If any follicle becomes too sensitive to androgens its suppressive action can become excessive for it.
DH? shows its suppressive action, influencing the growth phase of hair and making it vegetative. In general, every follicle can be in three various phases of life cycle, there are anagen, catagen and telogen. Anagen is a time when hair follicle creates hair. In anagen phase, which lasts some years, there are usually 85 % of hair follicles. Catagen is a time of degradation of a follicle. Hair growth stops, and hair root takes typical form of a bulb. This phase lasts during some weeks. In telogen phase hair gets detached from a root and slowly moves to the surface of a skin. In telogen phase there is approximately 15 % of hair. During combing and head washing you lose it. Normal loss makes 70-80 hairs per day.
From a final growth phase (Anagen) hair passes to the following stage Catagen. Internal segment separates from a papilla. Then bulb of the hair is pulled up to erector level (Telogen). Then hair growth stops, formation of new hair begins and, in phase of Anagen which comes again, growing hair “pushes out” a bulb of old hair.
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